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LC-MS Method for Studying the Pharmacokinetics and Bioequivalence of Clonidine Hydrochloride in Healthy Male Volunteers

BACKGROUND: A simple and sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been evaluated for the assignment of clonidine hydrochloride in human plasma. METHODS: The mobile phase composed of acetonitrile-water 60:40 (v/v) and 0.2% formic acid 20 μl...

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Bibliografiske detaljer
Udgivet i:Avicenna J Med Biotechnol
Main Authors: Danafar, Hossein, Hamidi, Mehrdad
Format: Artigo
Sprog:Inglês
Udgivet: Avicenna Research Institute 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842247/
https://ncbi.nlm.nih.gov/pubmed/27141268
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