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Keloids: The paradigm of skin fibrosis – pathomechanisms and treatment

Keloids, fibroproliferative dermal tumors with effusive accumulation of extracellular matrix (ECM) components, particularly collagen, result from excessive expression of growth factors and cytokines. The etiology of keloids is unknown but they occur after dermal injury in genetically susceptible ind...

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Bibliographic Details
Published in:Matrix Biol
Main Authors: Andrews, Jonathan P., Marttala, Jaana, Macarak, Edward, Rosenbloom, Joel, Uitto, Jouni
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842154/
https://ncbi.nlm.nih.gov/pubmed/26844756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.01.013
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