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INHIBITION OF TGFβ CELL SIGNALING IN RABBIT FOR LIMBAL EXPLANT CULTURE IN SERUMLESS, DEFINED XENO-FREE CONDITIONS

Outgrowths of limbal epithelium by explant culture are used to treat limbal stem cell deficiency (LSCD). The explant culture medium is always complemented with serum, a complex solution which includes TGFβ. Since TGFβ is a cytostatic effector for epithelial proliferation we examined its effect on th...

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Dettagli Bibliografici
Pubblicato in:Exp Eye Res
Autori principali: Zamudio, Aldo, Wang, Zheng, Chung, So-Hyang, Wolosin, J. Mario
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842090/
https://ncbi.nlm.nih.gov/pubmed/26554938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.10.021
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