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Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A

Human immunodeficiency virus 1 (HIV-1) multiplication depends on a cellular protein, cyclophilin A (CyPA), that gets integrated into viral particles. Because CyPA is not required for cell viability, we attempted to block its synthesis in order to inhibit HIV-1 replication. For this purpose, we used...

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Udgivet i:Nucleic Acids Res
Principais autores: Liu, Songkai, Asparuhova, Maria, Brondani, Vincent, Ziekau, Ingrid, Klimkait, Thomas, Schümperli, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC484190/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh715
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