False-positive Rifampin Resistant Results with Xpert MTB/RIF Version 4 Assay in clinical samples with a low bacterial load

We report investigation of 22 TB cases with positive Xpert MTB/RIF result for resistance to Rifampin and “Very Low” MTB detection level. Twelve cases were false positive without rpoB mutations, 2 were false-positives with a silent mutation in rpoB codon T508 and only 10 were true positives.

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Diagn Microbiol Infect Dis
Egile Nagusiak: Ocheretina, Oksana, Byrt, Erin, Mabou, Marie-Marcelle, Royal-Mardi, Gertrude, Merveille, Yves-Mary, Rouzier, Vanessa, Fitzgerald, Daniel W, Pape, Jean W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841693/
https://ncbi.nlm.nih.gov/pubmed/26915638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diagmicrobio.2016.01.009
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