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Fasciola hepatica Surface Coat Glycoproteins Contain Mannosylated and Phosphorylated N-glycans and Exhibit Immune Modulatory Properties Independent of the Mannose Receptor

Fascioliasis, caused by the liver fluke Fasciola hepatica, is a neglected tropical disease infecting over 1 million individuals annually with 17 million people at risk of infection. Like other helminths, F. hepatica employs mechanisms of immune suppression in order to evade its host immune system. I...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Ravidà, Alessandra, Aldridge, Allison M., Driessen, Nicole N., Heus, Ferry A. H., Hokke, Cornelis H., O’Neill, Sandra M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841591/
https://ncbi.nlm.nih.gov/pubmed/27104959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004601
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