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Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice.

Expression of the viral oncogene encoding the simian virus 40 (SV40) large tumor antigen (T antigen) typically promotes tumorigenesis in mammalian cells. To generate transgenic mice that express T antigen in rod photoreceptors, a chimeric construct consisting of a mouse opsin promoter fragment fused...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: al-Ubaidi, M R, Hollyfield, J G, Overbeek, P A, Baehr, W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1992
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48415/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1311085/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.4.1194
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