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Conjugation of insulin onto the sidewalls of single-walled carbon nanotubes through functionalization and diimide-activated amidation

PURPOSE: The high aspect ratio of carbon nanotubes (CNTs) allows the attachment of compounds that enhance the functionality of the drug vehicle. Considering this, use of CNTs as a multifunctional insulin carrier may be an interesting prospect to explore. MATERIALS AND METHODS: The carboxylic acid gr...

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Publicat a:Int J Nanomedicine
Autors principals: Ng, Chee Meng, Loh, Hwei-San, Muthoosamy, Kasturi, Sridewi, Nanthini, Manickam, Sivakumar
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841430/
https://ncbi.nlm.nih.gov/pubmed/27143882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S98726
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