Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study

Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was to develop a lecithin-based mixed polymeric micelle (LMPM) delivery system to improve the solubility and bioavailability of Que. Th...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Chen, Ling-Chun, Chen, Ying-Chen, Su, Chia-Yu, Hong, Chung-Shu, Ho, Hsiu-O, Sheu, Ming-Thau
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841422/
https://ncbi.nlm.nih.gov/pubmed/27143878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S103681
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