Therapeutic effects of glatiramer acetate and grafted CD115(+) monocytes in a mouse model of Alzheimer’s disease

Weekly glatiramer acetate immunization of transgenic mice modelling Alzheimer’s disease resulted in retained cognition (Morris water maze test), decreased amyloid-β plaque burden, and regulation of local inflammation through a mechanism involving enhanced recruitment of monocytes. Ablation of bone m...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Koronyo, Yosef, Salumbides, Brenda C., Sheyn, Julia, Pelissier, Lindsey, Li, Songlin, Ljubimov, Vladimir, Moyseyev, Michelle, Daley, David, Fuchs, Dieu-Trang, Pham, Michael, Black, Keith L., Rentsendorj, Altan, Koronyo-Hamaoui, Maya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840949/
https://ncbi.nlm.nih.gov/pubmed/26049087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv150
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