Evolutionary Paths That Expand Plasmid Host-Range: Implications for Spread of Antibiotic Resistance

The World Health Organization has declared the emergence of antibiotic resistance to be a global threat to human health. Broad-host-range plasmids have a key role in causing this health crisis because they transfer multiple resistance genes to a wide range of bacteria. To limit the spread of antibio...

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Bibliographic Details
Published in:Mol Biol Evol
Main Authors: Loftie-Eaton, Wesley, Yano, Hirokazu, Burleigh, Stephen, Simmons, Ryan S., Hughes, Julie M., Rogers, Linda M., Hunter, Samuel S., Settles, Matthew L., Forney, Larry J., Ponciano, José M., Top, Eva M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840908/
https://ncbi.nlm.nih.gov/pubmed/26668183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv339
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