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Efficient inhibition of human immunodeficiency virus replication using novel modified microRNA-30a targeting 3′-untranslated region transcripts

RNA interference (RNAi)-based gene therapy is currently considered to be a combinatorial anti-human immunodeficiency virus-1 (HIV-1) therapy. Although artificial polycistronic microRNAs (miRs) can reduce HIV-1 escape mutant variants, this approach may increase the risk of side effects. The present s...

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Publicado no:Exp Ther Med
Main Authors: NEJATI, AHMAD, SHAHMAHMOODI, SHOHREH, AREFIAN, EHSAN, SHOJA, ZABIHOLLAH, MARASHI, SAYED-MAHDI, TABATABAIE, HAMIDEH, MOLLAEI-KANDELOUS, YAGHOUB, SOLEIMANI, MASOUD, NATEGH, RAKHSHANDEH
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840495/
https://ncbi.nlm.nih.gov/pubmed/27168813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3121
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