Cholinergic Mesopontine Signals Govern Locomotion and Reward Through Dissociable Midbrain Pathways

The mesopontine tegmentum, including the pedunculopontine and laterodorsal tegmental nuclei (PPN and LDT), provides major cholinergic inputs to midbrain and regulates locomotion and reward. To delineate the underlying projection-specific circuit mechanisms we employed optogenetics to control mesopon...

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Publié dans:Neuron
Auteurs principaux: Xiao, Cheng, Cho, Jounhong Ryan, Zhou, Chunyi, Treweek, Jennifer B., Chan, Ken, McKinney, Sheri L., Yang, Bin, Gradinaru, Viviana
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840478/
https://ncbi.nlm.nih.gov/pubmed/27100197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.03.028
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