Cholinergic Mesopontine Signals Govern Locomotion and Reward Through Dissociable Midbrain Pathways

The mesopontine tegmentum, including the pedunculopontine and laterodorsal tegmental nuclei (PPN and LDT), provides major cholinergic inputs to midbrain and regulates locomotion and reward. To delineate the underlying projection-specific circuit mechanisms we employed optogenetics to control mesopon...

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Bibliographic Details
Published in:Neuron
Main Authors: Xiao, Cheng, Cho, Jounhong Ryan, Zhou, Chunyi, Treweek, Jennifer B., Chan, Ken, McKinney, Sheri L., Yang, Bin, Gradinaru, Viviana
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840478/
https://ncbi.nlm.nih.gov/pubmed/27100197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.03.028
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