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CTCF: making the right connections

The role of the zinc finger protein CTCF in organizing the genome within the nucleus is now well established. Widely separated sites on DNA, occupied by both CTCF and the cohesin complex, make physical contacts that create large loop domains. Additional contacts between loci within those domains, of...

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Publicat a:Genes Dev
Autors principals: Ghirlando, Rodolfo, Felsenfeld, Gary
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840295/
https://ncbi.nlm.nih.gov/pubmed/27083996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.277863.116
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