Gly482Ser PGC-1α Gene Polymorphism and Exercise-Related Oxidative Stress in Amyotrophic Lateral Sclerosis Patients

The role of exercise in Amyotrophic lateral sclerosis (ALS) pathogenesis is controversial and unclear. Exercise induces a pleiotropic adaptive response in skeletal muscle, largely through the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a transcriptional coactivator that reg...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Pasquinelli, Angelique, Chico, Lucia, Pasquali, Livia, Bisordi, Costanza, Lo Gerfo, Annalisa, Fabbrini, Monica, Petrozzi, Lucia, Marconi, Letizia, Caldarazzo Ienco, Elena, Mancuso, Michelangelo, Siciliano, Gabriele
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840260/
https://ncbi.nlm.nih.gov/pubmed/27147974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00102
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