The SafeBoosC II randomized trial: treatment guided by near-infrared spectroscopy reduces cerebral hypoxia without changing early biomarkers of brain injury

BACKGROUND: The SafeBoosC phase II multicentre randomized clinical trial investigated the benefits and harms of monitoring cerebral oxygenation by near-infrared spectroscopy (NIRS) combined with an evidence-based treatment guideline vs. no NIRS data and treatment as usual in the control group during...

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Veröffentlicht in:Pediatr Res
Hauptverfasser: Plomgaard, Anne M., van Oeveren, Wim, Petersen, Tue H., Alderliesten, Thomas, Austin, Topun, van Bel, Frank, Benders, Manon, Claris, Olivier, Dempsey, Eugene, Franz, Axel, Fumagalli, Monica, Gluud, Christian, Hagmann, Cornelia, Hyttel-Sorensen, Simon, Lemmers, Petra, Pellicer, Adelina, Pichler, Gerhard, Winkel, Per, Greisen, Gorm
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Clinical Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840238/
https://ncbi.nlm.nih.gov/pubmed/26679155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2015.266
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