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Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy.

Gene transfer into vascular smooth muscle cells in animals was examined by using recombinant retroviral vectors containing an Escherichia coli beta-galactosidase gene or a human adenosine deaminase (adenosine aminohydrolase, EC 3.5.4.4) gene. Direct gene transfer by infusion of virus into rat caroti...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lynch, C M, Clowes, M M, Osborne, W R, Clowes, A W, Miller, A D
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1736297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.3.1138
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