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Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors

The inevitable switch from standard molecular methods to next-generation sequencing for the molecular profiling of tumors is challenging for most diagnostic laboratories. However, fixed validation criteria for diagnostic accreditation are not in place because of the great variability in methods and...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Froyen, Guy, Broekmans, An, Hillen, Femke, Pat, Karin, Achten, Ruth, Mebis, Jeroen, Rummens, Jean-Luc, Willemse, Johan, Maes, Brigitte
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839685/
https://ncbi.nlm.nih.gov/pubmed/27101000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154038
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