Efficacy and safety of thalidomide for the treatment of severe recurrent epistaxis in hereditary hemorrhagic telangiectasia: results of a prospective phase II clinical trial

BACKGROUND: Hereditary hemorrhagic telangiectasia (HHT) is a genetic disease that leads to multiregional angiodysplasia. Severe recurrent epistaxis is the most common presentation, frequently leading to severe anemia. Multiple therapeutic approaches have been tried, but they are largely palliative w...

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Detalhes bibliográficos
Publicado no:Lancet Haematol
Main Authors: Invernizzi, Rosangela, Quaglia, Federica, Klersy, Caherine, Pagella, Fabio, Ornati, Federica, Chu, Francesco, Matti, Elina, Spinozzi, Giuseppe, Plumitallo, Sara, Grignani, Pierangela, Olivieri, Carla, Bastia, Raffaella, Bellistri, Francesca, Danesino, Cesare, Benazzo, Marco, Balduini, Carlo L
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839500/
https://ncbi.nlm.nih.gov/pubmed/26686256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(15)00195-7
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