Efficacy and safety of thalidomide for the treatment of severe recurrent epistaxis in hereditary hemorrhagic telangiectasia: results of a prospective phase II clinical trial

BACKGROUND: Hereditary hemorrhagic telangiectasia (HHT) is a genetic disease that leads to multiregional angiodysplasia. Severe recurrent epistaxis is the most common presentation, frequently leading to severe anemia. Multiple therapeutic approaches have been tried, but they are largely palliative w...

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Gepubliceerd in:Lancet Haematol
Hoofdauteurs: Invernizzi, Rosangela, Quaglia, Federica, Klersy, Caherine, Pagella, Fabio, Ornati, Federica, Chu, Francesco, Matti, Elina, Spinozzi, Giuseppe, Plumitallo, Sara, Grignani, Pierangela, Olivieri, Carla, Bastia, Raffaella, Bellistri, Francesca, Danesino, Cesare, Benazzo, Marco, Balduini, Carlo L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839500/
https://ncbi.nlm.nih.gov/pubmed/26686256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(15)00195-7
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