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Overexpression of KIR inhibitory ligands (HLA-I) determines that immunosurveillance of myeloma depends on diverse and strong NK cell licensing
Missing self recognition makes cancer sensitive to natural killer cell (NKc) reactivity. However, this model disregards the NKc licensing effect, which highly increases NKc reactivity through interactions of inhibitory killer cell immunoglobulin-like receptors (iKIR) with their cognate HLA-I ligands...
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Foilsithe in: | Oncoimmunology |
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Main Authors: | , , , , , , , , , , , , , , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Taylor & Francis
2015
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839374/ https://ncbi.nlm.nih.gov/pubmed/27141379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1093721 |
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