CD137 and CD137L signals are main drivers of type 1, cell-mediated immune responses

CD137 is expressed on activated T cells and NK cells, among others, and is a potent co-stimulator of antitumor immune responses. CD137 ligand (CD137L) is expressed by antigen presenting cells (APC), and CD137L reverse signaling into APC enhances their activity. CD137–CD137L interactions as main driv...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Dharmadhikari, Bhushan, Wu, Meihui, Abdullah, Nur Sharalyn, Rajendran, Sakthi, Ishak, Nur Diana, Nickles, Emily, Harfuddin, Zulkarnain, Schwarz, Herbert
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839363/
https://ncbi.nlm.nih.gov/pubmed/27141396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1113367
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