High-dose chemotherapy and autologous stem cell transplant compared with conventional chemotherapy for consolidation in newly diagnosed primary CNS lymphoma—a randomized phase III trial (MATRix)

BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a highly aggressive Non-Hodgkin lymphoma (NHL) with rising incidence over the past 30 years in immunocompetent patients. Although outcomes have improved, PCNSL is still associated with inferior prognosis compared to systemic NHL. Many qu...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Schorb, Elisabeth, Finke, Juergen, Ferreri, Andrés J. M., Ihorst, Gabriele, Mikesch, Kristina, Kasenda, Benjamin, Fritsch, Kristina, Fricker, Heidi, Burger, Elvira, Grishina, Olga, Valk, Elke, Zucca, Emanuele, Illerhaus, Gerald
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Study Protocol
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839072/
https://ncbi.nlm.nih.gov/pubmed/27098429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2311-4
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