Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas

Oligodendroglial tumours (OT) are a heterogeneous group of gliomas. Three molecular subgroups are currently distinguished on the basis of the IDH mutation and 1p/19q co-deletion. Here we present an integrated analysis of the transcriptome, genome and methylome of 156 OT. Not only does our multi-omic...

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Udgivet i:Nat Commun
Main Authors: Kamoun, Aurélie, Idbaih, Ahmed, Dehais, Caroline, Elarouci, Nabila, Carpentier, Catherine, Letouzé, Eric, Colin, Carole, Mokhtari, Karima, Jouvet, Anne, Uro-Coste, Emmanuelle, Martin-Duverneuil, Nadine, Sanson, Marc, Delattre, Jean-Yves, Figarella-Branger, Dominique, de Reyniès, Aurélien, Ducray, François
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838899/
https://ncbi.nlm.nih.gov/pubmed/27090007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11263
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