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Aurora A drives early signalling and vesicle dynamics during T-cell activation
Aurora A is a serine/threonine kinase that contributes to the progression of mitosis by inducing microtubule nucleation. Here we have identified an unexpected role for Aurora A kinase in antigen-driven T-cell activation. We find that Aurora A is phosphorylated at the immunological synapse (IS) durin...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4838898/ https://ncbi.nlm.nih.gov/pubmed/27091106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11389 |
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