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Pyruvate Kinase M2: A Potential Target for Regulating Inflammation

Pyruvate kinase (PK) is the enzyme responsible for catalyzing the last step of glycolysis. Of the four PK isoforms expressed in mammalian cells, PKM2 has generated the most interest due to its impact on changes in cellular metabolism observed in cancer as well as in activated immune cells. As our un...

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Vydáno v:Front Immunol
Hlavní autoři: Alves-Filho, Jose C., Pålsson-McDermott, Eva M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838608/
https://ncbi.nlm.nih.gov/pubmed/27148264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00145
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