Model-based evaluation of cost-effectiveness of Nerve Growth Factor Inhibitors in Knee Osteoarthritis: Impact of drug cost, toxicity, and means of administration

OBJECTIVE: Studies suggest nerve growth factor inhibitors (NGFi) relieve pain but may accelerate disease progression in some patients with osteoarthritis (OA). We sought cost and toxicity thresholds that would make NGFi a cost-effective treatment for moderate-to-severe knee OA. DESIGN: We used the O...

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Vydáno v:Osteoarthritis Cartilage
Hlavní autoři: Losina, Elena, Michl, Griffin, Collins, Jamie E., Hunter, David J., Jordan, Joanne M., Yelin, Edward, Paltiel, A. David, Katz, Jeffrey N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838505/
https://ncbi.nlm.nih.gov/pubmed/26746146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.12.011
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