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Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer’s disease

We have previously reported in Alzheimer’s disease (AD) the mislocalization of epigenetic molecules between the cell nucleus and the cytoplasm. We have extended our finding to include the aberrant localization of histone 3 trimethylation on lysine 4 (H3k4me3), an epigenetic mark associated with acti...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Mastroeni, Diego, Delvaux, Elaine, Nolz, Jennifer, Tan, Yuyan, Grover, Andrew, Oddo, Salvatore, Coleman, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838454/
https://ncbi.nlm.nih.gov/pubmed/26553823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.08.017
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