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TopDom: an efficient and deterministic method for identifying topological domains in genomes

Genome-wide proximity ligation assays allow the identification of chromatin contacts at unprecedented resolution. Several studies reveal that mammalian chromosomes are composed of topological domains (TDs) in sub-mega base resolution, which appear to be conserved across cell types and to some extent...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Shin, Hanjun, Shi, Yi, Dai, Chao, Tjong, Harianto, Gong, Ke, Alber, Frank, Zhou, Xianghong Jasmine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838359/
https://ncbi.nlm.nih.gov/pubmed/26704975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1505
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