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B16/F10 tumors in aged 3D collagen in vitro simulate tumor growth and gene expression in aged mice in vivo

Although the incidence of cancer rises with age, tumor growth is often slowed in older hosts. The B16/F10 melanoma cell line is commonly used in murine models of age-related tumor growth suppression. We wished to determine if the growth pattern and gene expression of B16/10 tumors grown in aged mice...

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Pubblicato in:In Vitro Cell Dev Biol Anim
Autori principali: Bentov, Itay, Damodarasamy, Mamatha, Plymate, Stephen, Reed, May J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838284/
https://ncbi.nlm.nih.gov/pubmed/23661088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-013-9623-3
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