Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer Genomics

Retroviruses have been foundational in cancer research since early studies identified proto-oncogenes as targets for insertional mutagenesis. Integration of murine gamma-retroviruses into the host genome favours promoters and enhancers and entails interaction of viral integrase with host BET/bromodo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gilroy, Kathryn L., Terry, Anne, Naseer, Asif, de Ridder, Jeroen, Allahyar, Amin, Wang, Weiwei, Carpenter, Eric, Mason, Andrew, Wong, Gane K-S., Cameron, Ewan R., Kilbey, Anna, Neil, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838236/
https://ncbi.nlm.nih.gov/pubmed/27097319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154070
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