Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression

Traditional toxicological paradigms have relied on factors such as age, genotype, and disease status to explain variability in responsiveness to toxicant exposure; however, these are neither sufficient to faithfully identify differentially responsive individuals nor are they modifiable factors that...

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Bibliographic Details
Published in:Toxicol Sci
Main Authors: McCullough, Shaun D., Bowers, Emma C., On, Doan M., Morgan, David S., Dailey, Lisa A., Hines, Ronald N., Devlin, Robert B., Diaz-Sanchez, David
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Chromatin Modification and Gene Expression after Ozone Exposure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838038/
https://ncbi.nlm.nih.gov/pubmed/26719369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv324
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