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Development and characterization of novel 8-plex DiLeu isobaric labels for quantitative proteomics and peptidomics

RATIONALE: Relative quantification of proteins via their enzymatically digested peptide products determines disease biomarker candidate lists in discovery studies. Isobaric label-based strategies using TMT and iTRAQ allow for up to 10 samples to be multiplexed in one experiment, but their expense li...

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Veröffentlicht in:Rapid Commun Mass Spectrom
Hauptverfasser: Frost, Dustin C., Greer, Tyler, Xiang, Feng, Liang, Zhidan, Li, Lingjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837894/
https://ncbi.nlm.nih.gov/pubmed/25981542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.7201
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