Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS

The signaling pathways that regulate myelination in the PNS remain poorly understood. Phosphatidylinositol-4,5-bisphosphate 3-kinase 1A, activated in Schwann cells by neuregulin and the extracellular matrix, has an essential role in the early events of myelination. Akt/PKB, a key effector of phospha...

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Publicat a:J Neurosci
Autors principals: Domènech-Estévez, Enric, Baloui, Hasna, Meng, Xiaosong, Zhang, Yanqing, Deinhardt, Katrin, Dupree, Jeff L., Einheber, Steven, Chrast, Roman, Salzer, James L.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837684/
https://ncbi.nlm.nih.gov/pubmed/27098694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3521-15.2016
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