BRAF V600 mutations in Langerhans cell histiocytosis with a simple and unique assay

BACKGROUND: BRAF (V-raf murine sarcoma viral oncogene homolog B1) is a serine-threonine protein kinase involved in cell survival, proliferation, and differentiation. The most common missense mutation of BRAF (mainly V600E) contributes to the incidence of various cancers, including Langerhans cell hi...

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Bibliografiske detaljer
Udgivet i:Diagn Pathol
Main Authors: Tatsuno, Michiko, Shioda, Yoko, Iwafuchi, Hideto, Yamazaki, Shigeki, Iijima, Kenta, Takahashi, Chiaki, Ono, Hiromi, Uchida, Kiyono, Okamura, Osamu, Matubayashi, Mamoru, Okuyama, Torayuki, Matsumoto, Kimikazu, Yoshioka, Takako, Nakazawa, Atsuko
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837618/
https://ncbi.nlm.nih.gov/pubmed/27094161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-016-0489-z
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