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Levels of human platelet-derived soluble CD40 ligand depend on haplotypes of CD40LG-CD40-ITGA2

Increased circulating soluble CD40 ligand (sCD40L) is commonly associated with inflammatory disorders. We aimed to investigate whether gene polymorphisms in CD40LG, CD40 and ITGA2 are associated with a propensity to secrete sCD40L; thus, we examined this issue at the level of human platelets, the pr...

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Publicado en:Sci Rep
Main Authors: Aloui, Chaker, Prigent, Antoine, Tariket, Sofiane, Sut, Caroline, Fagan, Jocelyne, Cognasse, Fabrice, Chakroun, Tahar, Garraud, Olivier, Laradi, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837387/
https://ncbi.nlm.nih.gov/pubmed/27094978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24715
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