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A putative nitroreductase from the DosR regulon of Mycobacterium tuberculosis induces pro-inflammatory cytokine expression via TLR2 signaling pathway

Tuberculosis caused by Mycobacterium tuberculosis is a global encumbrance and it is estimated that nearly one third population of the world acts as a reservoir for this pathogen without any symptoms. In this study, we attempted to characterise one of the genes of DosR regulon, Rv3131, a FMN binding...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Peddireddy, Vidyullatha, Doddam, Sankara Narayana, Qureshi, Insaf A., Yerra, Priyadarshini, Ahmed, Niyaz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837367/
https://ncbi.nlm.nih.gov/pubmed/27094446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24535
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