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Adaptive evolution of degrees and kinds of neoplastic transformation in cell culture.

Human cancers undergo protracted complex development from benign to malignant states, as most thoroughly documented in the mole-to-melanoma sequence. The early stages of the sequence tend to redifferentiate into normal tissues; the later stages progress to ever increasing multiplication and malignan...

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Publicat a:Proc Natl Acad Sci U S A
Autor principal: Rubin, H
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48368/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1736314/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.3.977
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