Weight and Glucose Reduction Observed with a Combination of Nutritional Agents in Rodent Models Does Not Translate to Humans in a Randomized Clinical Trial with Healthy Volunteers and Subjects with Type 2 Diabetes

BACKGROUND: Nutritional agents have modest efficacy in reducing weight and blood glucose in animal models and humans, but combinations are less well characterized. GSK2890457 (GSK457) is a combination of 4 nutritional agents, discovered by the systematic assessment of 16 potential components using t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hodge, Rebecca J., Paulik, Mark A., Walker, Ann, Boucheron, Joyce A., McMullen, Susan L., Gillmor, Dawn S., Nunez, Derek J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836696/
https://ncbi.nlm.nih.gov/pubmed/27093610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153151
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