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APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone

The hallmarks of Alzheimer’s disease (AD) are characterized by cognitive decline and behavioral changes. The most prominent brain region affected by the progression of AD is the hippocampal formation. The pathogenesis involves a successive loss of hippocampal neurons accompanied by a decline in lear...

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Foilsithe in:PLoS Comput Biol
Main Authors: Laßek, Melanie, Weingarten, Jens, Wegner, Martin, Mueller, Benjamin F., Rohmer, Marion, Baeumlisberger, Dominic, Arrey, Tabiwang N., Hick, Meike, Ackermann, Jörg, Acker-Palmer, Amparo, Koch, Ina, Müller, Ulrike, Karas, Michael, Volknandt, Walter
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836664/
https://ncbi.nlm.nih.gov/pubmed/27092780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004832
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