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Ubiquitous accumulation of 3′ mRNA decay fragments in Saccharomyces cerevisiae mRNAs with chromosomally integrated MS2 arrays

The binding of MS2-GFP protein to arrays of MS2 sites in yeast mRNAs has been used extensively to visualize mRNA localization. We previously reported that arrays of MS2 sites bound by MS2 protein could inhibit Xrn1p and lead to the accumulation of 3′ mRNA decay fragments. We suggest that these decay...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Garcia, Jennifer F., Parker, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836640/
https://ncbi.nlm.nih.gov/pubmed/27090788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.056325.116
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