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Effects of high glucose on caveolin-1 and insulin signaling in 3T3-L1 adipocytes

Adipocytes exposed to high glucose concentrations exhibit impaired metabolic function, including an increase of oxidative and proinflammatory factors that might favor the development of insulin resistance. Caveolin-1 (Cav-1) is a key mediator of the insulin transduction pathway whose expression is s...

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Detalhes bibliográficos
Publicado no:Adipocyte
Main Authors: Palacios-Ortega, Sara, Varela-Guruceaga, Maider, Martínez, J. Alfredo, de Miguel, Carlos, Milagro, Fermín I.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836491/
https://ncbi.nlm.nih.gov/pubmed/27144098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21623945.2015.1122856
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