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Influenza A Virus Dysregulates Host Histone Deacetylase 1 That Inhibits Viral Infection in Lung Epithelial Cells

Viruses dysregulate the host factors that inhibit virus infection. Here, we demonstrate that human enzyme, histone deacetylase 1 (HDAC1) is a new class of host factor that inhibits influenza A virus (IAV) infection, and IAV dysregulates HDAC1 to efficiently replicate in epithelial cells. A time-depe...

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Vydáno v:J Virol
Hlavní autoři: Nagesh, Prashanth Thevkar, Husain, Matloob
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836332/
https://ncbi.nlm.nih.gov/pubmed/26912629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00126-16
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