Recovery of West Nile Virus Envelope Protein Domain III Chimeras with Altered Antigenicity and Mouse Virulence

Flaviviruses are positive-sense, single-stranded RNA viruses responsible for millions of human infections annually. The envelope (E) protein of flaviviruses comprises three structural domains, of which domain III (EIII) represents a discrete subunit. The EIII gene sequence typically encodes epitopes...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: McAuley, Alexander J., Torres, Maricela, Plante, Jessica A., Huang, Claire Y.-H., Bente, Dennis A., Beasley, David W. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836310/
https://ncbi.nlm.nih.gov/pubmed/26912625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02861-15
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