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A single-arm phase II trial of pazopanib in patients with advanced non-small cell lung cancer with non-squamous histology with disease progression on bevacizumab containing therapy

OBJECTIVES: Platinum-based chemotherapy with bevacizumab is a standard therapy for patients with stage IIIB/IV non-small cell lung cancer (NSCLC) with non-squamous (NS) histology. Mechanisms of resistance to bevacizumab include increased VEGF signaling or activation of VEGF receptors. Pazopanib is a...

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Bibliografski detalji
Izdano u:Lung Cancer
Glavni autori: Weiss, Jared M., Villaruz, Liza C., Socinski, Mark A., Ivanova, Anastasia, Grilley-Olson, Juneko, Dhruva, Nirav, Stinchcombe, Thomas E.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836183/
https://ncbi.nlm.nih.gov/pubmed/25201721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2014.08.011
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