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Inhibition of BMI1 induces autophagy-mediated necroptosis
The clonal self-renewal property conferred by BMI1 is instrumental in maintenance of not only normal stem cells but also cancer-initiating cells from several different malignancies that represent a major challenge to chemotherapy. Realizing the immense pathological significance, PTC-209, a small mol...
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| Veröffentlicht in: | Autophagy |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836029/ https://ncbi.nlm.nih.gov/pubmed/27050456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1147670 |
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