Metabonomic profiles delineate potential role of glutamate-glutamine cycle in db/db mice with diabetes-associated cognitive decline

BACKGROUND: Diabetes-associated cognition decline is one of central nervous system complications in diabetic mellitus, while its pathogenic mechanism remains unclear. In this study, (1)H nuclear magnetic resonance-based metabonomics and immunohistochemistry was used to explore key metabolic alterati...

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Udgivet i:Mol Brain
Main Authors: Zheng, Yongquan, Yang, Yunjun, Dong, Baijun, Zheng, Hong, Lin, Xiaodong, Du, Yao, Li, Xiaokun, Zhao, Liangcai, Gao, Hongchang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835835/
https://ncbi.nlm.nih.gov/pubmed/27090642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0223-5
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