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Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea

Hydroxyurea (HU) has traditionally been the first-line treatment for patients with PV or ET at high-risk for vascular complications. However, approximately 20-25% of patients develop resistance or intolerance to HU and must be treated with second-line therapies. Resistance is associated with disease...

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Detalhes bibliográficos
Publicado no:Leuk Lymphoma
Main Authors: Sever, Matjaz, Newberry, Kate J., Verstovsek, Srdan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835800/
https://ncbi.nlm.nih.gov/pubmed/24524340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2014.893310
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