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Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts

Abnormally high activation of transforming growth factor-β (TGF-β) signaling has been demonstrated to be involved in the initiation and progression of keloids. However, the functional role of long non-coding RNA (lncRNA)-activated by TGF-β (lncRNA-ATB) in keloids has not been documented. Here we inv...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Zhu, Hua-Yu, Bai, Wen-Dong, Li, Chao, Zheng, Zhao, Guan, Hao, Liu, Jia-Qi, Yang, Xue-Kang, Han, Shi-Chao, Gao, Jian-Xin, Wang, Hong-Tao, Hu, Da-Hai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835760/
https://ncbi.nlm.nih.gov/pubmed/27090737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24728
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