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A large family of Dscam genes with tandemly arrayed 5′ cassettes in Chelicerata
Drosophila Dscam1 (Down Syndrome Cell Adhesion Molecules) and vertebrate clustered protocadherins (Pcdhs) are two classic examples of the extraordinary isoform diversity from a single genomic locus. Dscam1 encodes 38,016 distinct isoforms via mutually exclusive splicing in D. melanogaster, while the...
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發表在: | Nat Commun |
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Main Authors: | , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Nature Publishing Group
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835542/ https://ncbi.nlm.nih.gov/pubmed/27080167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11252 |
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